Cancer is a genetic disease caused by mutations in individual cells which cause them to no longer be governed by normal processes of growth and death within the organism. At Cold Spring Harbor we are focusing on many aspects of cancer. Our lab focuses on the genetic variants involving the progression of cancer. In doing this we have looked at a number of different types of cancer to better understand the process by which after cancer is initiated, the cancer cells grow and become metastatic. Recently we are focusing on how we can improve the resolution with which we understand the cancer genome. We are doing this with a combination of using long-read sequencing and the analysis of single cells. The long-term goal of this research is to identify steps within this process can be attacked with drugs to treat the cancer.
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